Gastrointestinal Cancer
Latest News
Advertisement
Latest Videos
CME Content
Advertisement
More News
The addition of selective internal radiation therapy with Y90 resin microspheres to gemcitabine/cisplatin resulted in a median overall survival of 21.6 months for patients with inoperable intrahepatic cholangiocarcinoma, according to prospective phase 2 data.
Combining durvalumab and tremelimumab plus transcatheter arterial chemoembolization or radiofrequency ablation was found to be both efficacious and safe as a treatment for patients with advanced hepatocellular carcinoma, according to results of a pilot study.
Josep M. Llovet, MD, discusses the importance of identifying biomarkers of response to checkpoint inhibitors for patients with hepatocellular carcinoma, as well as future research directions.
Devimistat in combination with gemcitabine and cisplatin has moved into the phase 2 portion of a phase 1b/2 trial studying the regimen as a first-line treatment for patients with locally advanced unresectable or metastatic biliary tract cancer.
William P. Harris, MD, discusses updated data from the phase 3 IMbrave150 study in hepatocellular carcinoma.
Systemic Treatment Advances for Advanced HCC
ByTanios S. Bekaii-Saab, MD, FACP, Mayo Clinic,Edward Kim, MD, Mount Sinai Medical Center,Anjana Pillai, MD, University of Chicago Medicine Comprehensive Cancer Center,Amit Singal, MD, UT Southwestern Medical Center,Rachna Shroff, MD, University of Arizona,Arndt Vogel, MD, Hannover Medical School,Mark Yarchoan, MD
Exciting developments using novel therapies as systemic treatment for advanced hepatocellular carcinoma.
Scoring/Classifying Patients With Advanced HCC
ByTanios S. Bekaii-Saab, MD, FACP, Mayo Clinic,Edward Kim, MD, Mount Sinai Medical Center,Anjana Pillai, MD, University of Chicago Medicine Comprehensive Cancer Center,Amit Singal, MD, UT Southwestern Medical Center,Rachna Shroff, MD, University of Arizona,Arndt Vogel, MD, Hannover Medical School,Mark Yarchoan, MD
Best practices using available scoring systems to evaluate and treat patients with advanced hepatocellular carcinoma.
E. Gabriela Chiorean, MD, discusses the role of molecular testing in pancreatic cancer.
The combination of cabozantinib and nivolumab as a neoadjuvant regimen led to encouraging margin-negative resection and major pathological response rates in patients with hepatocellular carcinoma, according to results of a single-arm, phase 1b study that were published in Nature Cancer.
The FDA has granted an orphan drug designation to gavocabtagene autoleucel as a potential treatment for patients with cholangiocarcinoma.
Adjuvant Treatment Advances in Operable HCC
ByTanios S. Bekaii-Saab, MD, FACP, Mayo Clinic,Edward Kim, MD, Mount Sinai Medical Center,Anjana Pillai, MD, University of Chicago Medicine Comprehensive Cancer Center,Amit Singal, MD, UT Southwestern Medical Center,Rachna Shroff, MD, University of Arizona,Arndt Vogel, MD, Hannover Medical School,Mark Yarchoan, MD
Perspectives regarding treatment advances using adjuvant approaches that include immunotherapy to treat early-stage hepatocellular carcinoma.
Hepatic Arterial Infusion Chemotherapy for HCC
ByTanios S. Bekaii-Saab, MD, FACP, Mayo Clinic,Edward Kim, MD, Mount Sinai Medical Center,Anjana Pillai, MD, University of Chicago Medicine Comprehensive Cancer Center,Amit Singal, MD, UT Southwestern Medical Center,Rachna Shroff, MD, University of Arizona,Arndt Vogel, MD, Hannover Medical School,Mark Yarchoan, MD
Reactions to recent clinical abstracts that support the use of hepatic arterial infusions for chemotherapy delivery in hepatocellular carcinoma.
Dr. Janjigian discusses the FDA approval of nivolumab plus chemotherapy in advanced or metastatic gastric cancer, gastroesophageal junction cancer, and esophageal adenocarcinoma, key findings from the pivotal CheckMate-649 trial, and future directions with immunotherapy in the field.
The FDA has approved the Oncomine Dx Target Test, developed by Thermo Fisher Scientific, for use as a companion diagnostic to identify patients with IDH1-mutated cholangiocarcinoma who may be eligible to receive the newly approved IDH1 inhibitor ivosidenib.
The FDA has approved ivosidenib for the treatment of adult patients with previously treated, locally advanced or metastatic cholangiocarcinoma with an IDH1 mutation, as detected by an FDA-approved test.
Merck KGaA, Darmstadt, Germany has decided to discontinue the phase 2 INTR@PID BTC 055 trial examining bintrafusp alfa plus gemcitabine and cisplatin in the frontline treatment of patients with locally advanced or metastatic biliary tract cancer.
John L. Marshall, MD; Marwan G. Fakih, MD; and Joleen M. Hubbard, MD, highlight novel strategies in the metastatic colorectal cancer pipeline that look exciting and consider their integration into future clinical practice.
The rationale for continuing to study the combination of immunotherapies with novel tyrosine kinase inhibitors in metastatic colorectal cancer.
If there is one touchstone that emerges from Dr. Margaret A. Tempero's career of studying and treating pancreatic cancer, it is her persistence in simply trying to help her patients.
Neoadjuvant Therapy to Downstage HCC
ByTanios S. Bekaii-Saab, MD, FACP, Mayo Clinic,Edward Kim, MD, Mount Sinai Medical Center,Anjana Pillai, MD, University of Chicago Medicine Comprehensive Cancer Center,Amit Singal, MD, UT Southwestern Medical Center,Rachna Shroff, MD, University of Arizona,Arndt Vogel, MD, Hannover Medical School,Mark Yarchoan, MD
Reactions to treatment gaps in the neoadjuvant space for hepatocellular carcinoma and implications for incorporating data supporting newer, novel systemic therapies for appropriate patients.
Advances in Locoregional Therapy for Early Stage HCC
ByTanios S. Bekaii-Saab, MD, FACP, Mayo Clinic,Edward Kim, MD, Mount Sinai Medical Center,Anjana Pillai, MD, University of Chicago Medicine Comprehensive Cancer Center,Amit Singal, MD, UT Southwestern Medical Center,Rachna Shroff, MD, University of Arizona,Arndt Vogel, MD, Hannover Medical School,Mark Yarchoan, MD
University of Arizona’s Rachna Shroff, MD, describes the role of systemic therapy with locoregional treatment for early stage hepatocellular carcinoma and highlights treatment strategies of interest that remain under investigation.
The FDA has granted an orphan drug designation to LP-184 as a potential therapeutic option for patients with pancreatic cancer.
The European Medicines Agency has validated its Type II Variation Marketing Authorization Applications for nivolumab plus ipilimumab and nivolumab plus fluoropyrimidine- and platinum-containing chemotherapy as frontline options for adult patients with unresectable advanced, recurrent, or metastatic esophageal squamous cell carcinoma.
Implications for using the combination of pembrolizumab and lenvatinib to treat patients with metastatic colorectal cancer based on updated data from the LEAP-005 study.
Considerations for treating patients with metastatic colorectal cancer with the combination of nivolumab and regorafenib based on preliminary data.
Advertisement
Advertisement
Trending on OncLive
1
ASCO Guideline Update Broadens First-Line Treatment Options for HER2+ Gastroesophageal Cancer
2
CAR T-Cell Therapy Continues to Make Its Case in Early Relapsed Myeloma
3
FDA Awards Fast Track Designation to Safusidenib in IDH1-Mutant Glioma
4
ASCO Issues First Guideline on ctDNA Testing in Solid Tumors and Lymphoma
5